International Circulation: Treatment options for left main and multivessel coronary artery disease has been a hot topic for many years and many studies in this area have been published. Can you please summarize the major principle to which we should adhere to when choosing between CABG and PCI for patients with left main and multivessel coronary artery disease?
　Prof. Serruys: The patient wants to be pain-free without angina pectoris and without functional limitation. The two potential ways to achieve this are surgery with some comorbities and percutaneous intervention， which has less comorbidity but potentially more long-term risk. Therefore， it is a balance between short-term benefit and long-term risk. Fortunately， in some of the subsets of patients with main stem， for instance， patients with a Syntax score below 22 then it seems there is equality at least for a period of 3 years， not only in terms of mortality， myocardial infarction， stroke， a combination of those three， and revascularization then the two therapies are pretty much equal.